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Alternate Names: G1T28 dihydrochloride, Cosela, trilaciclib 2HCl
CAS No: 1977495-97-8
PubChem CID: 124081865
Mol Formula: C24H32Cl2N8O
Mol Weight: 519.5 g/mol
IUPAC Name: 4-[[5-(4-methylpiperazin-1-yl)pyridin-2-yl]amino]spiro[1,3,5,11-tetrazatricyclo[7.4.0.02,7]trideca-2,4,6,8-tetraene-13,1′-cyclohexane -Show More
Drug Class: CDK4/6 Inhibitors
Commercial / Development Status: Commercial APIs
API Description: Trilaciclib dihydrochloride is used to reduce the risk of chemotherapy-induced bone marrow suppression (myelosuppression) in patients with small cell lung cancer (SCLC). It is a CDK4/6 inhibitor that protects healthy bone marrow cells by temporarily blocking them from entering the cell cycle during chemotherapy. This helps lower the incidence of neutropenia, anemia, and thrombocytopenia caused by chemotherapy. It is administered before chemotherapy to preserve immune function and improve patient outcomes.
