Cyclin-dependent kinase 4 and 6 (CDK4/6) inhibitors are targeted anticancer agents that inhibit CDK4 and CDK6, key enzymes controlling progression of cells from the G1 phase → S phase of the cell cycle. They are particularly important in hormone receptor–positive (HR+), HER2-negative breast cancer. The following is a list of APIs used as CDK4/6 Inhibitors.
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