Find verified Ambrisentan API manufacturers, suppliers, and distributors across the globe. Explore companies that offer high-purity Ambrisentan for pharmaceutical use, along with product details, certifications, and reliable sourcing options. Compare prices, check availability, and connect directly with trusted suppliers for Ambrisentan API.
Alternate Names: Volibris, Letairis
CAS No: 177036-94-1
Mol Formula: C₂₂H₂₂N₂O₄
Mol Weight: 378.41 g/mol
IUPAC Name: (2S)-2-(4,6-dimethylpyrimidin-2-yl)oxy-3-methoxy-3,3-dipheny propanoic acid - Show More
API Description: Ambrisentan is an endothelin receptor antagonist used to treat pulmonary arterial hypertension. It works by relaxing blood vessels and reducing blood pressure in the lungs, improving exercise capacity. Ambrisentan is an orally active selective type A endothelin receptor antagonist indicated for the treatment of pulmonary arterial hypertension. It is approved in Europe, Canada and the United States for use as a single agent to improve exercise ability and delay clinical worsening. In addition, it is approved in the United States for use in combination with tadalafil to reduce the risks of disease progression, hospitalization and to improve exercise ability. Studies establishing the efficacy of Ambrisentan included patients with both idiopathic or heritable pulmonary arterial hypertension and those with pulmonary arterial hypertension associated with connective tissue diseases. Patients studied displayed symptoms and etiologies predominantly of WHO Functional Class II-III. As an endothelin receptor antagonist, Ambrisentan prevents endogenous endothelin peptide from constricting the muscles in blood vessels, allowing them to relax and permit a reduction in blood pressure.
Cipla is a global pharmaceutical company whose goal is ensuring no patient shall be denied access to high quality & affordable medicine and support. Mission: Cipla’s mission is to be a leading global healthcare company which uses technology and innovation to meet everyday need of all patients. Since inception in 1935, caring has been at the core of everything we do at Cipla. For patients, caring is a promise that we...Cipla is a global pharmaceutical company whose goal is ensuring no patient shall be denied access to high quality & affordable medicine and support. Mission: Cipla’s mission is to be a leading global healthcare company which uses technology and innovation to meet everyday needs of all patients. Since inception in 1935, caring has been at the core of everything we do at Cipla. For patients, caring is a promise that we will do whatever it takes to ensure they have continued access to the highest quality medicines at affordable prices; whether a disease affects millions or just a few hundreds.Cipla has built API process development at three locations in India, with dedicated teams working on synthetic, organic chemistry, process engineering and analytical development at multiple locations.Cipla API pipeline consists of 75+ complex developments in the therapy areas of Oncology, Hep C, ARV, Diabetology, CVS, CNS, Respiratory etc. - Show More
Zhejiang Huahai Pharmaceutical Co., Ltd., founded in 1989, is a leading pharmaceutical company headquartered in Linhai, Zhejiang, China. It specializes in the research, development, production, and sales of active pharmaceutical ingredients (APIs), intermediates, and formulated d sage forms. The company focuses on therapeutic areas such as cardiovascular, psychiatric, antiviral, antihistamine, and anti-HIV medications. - Show More
MSN Laboratories Private Limited is a leading, research-driven, and fully integrated pharmaceutical company headquartered in Hyderabad, Telangana, India. Established in 2003, MSN Laboratories has rapidly grown to become one of the fastest-growing pharmaceutical companies in the c untry, with a strong global presence. - Show More
Weijie group was founded in March 2003. By that time, with a hundred thousand RMB as registered capital, Dr.Song Honghai leaded a four-person team and began his venture. In 2013, after ten years of development, Weijie has developed into a series of companies which are involved in R&D, production, trading and sales of pharmaceutical intermediates and APIs. The four-person team has turned into a 200 employees who interact with e...Weijie group was founded in March 2003. By that time, with a hundred thousand RMB as registered capital, Dr.Song Honghai leaded a four-person team and began his venture. In 2013, after ten years of development, Weijie has developed into a series of companies which are involved in R&D, production, trading and sales of pharmaceutical intermediates and APIs. The four-person team has turned into a 200 employees who interact with each other actively for the running of the whole group. Weijie’s management team is open and internationalized. We have oversea employees from US and Italy in the top management, who have tremendous experiences in global pharmaceutical marketand bringing international views to a Chinese company. - Show More
Megafine Pharma Private Limited is a privately owned, professionally managed pharmaceutical company headquartered in Mumbai, India. Established in 1995, Megafine specializes in the manufacturing of Active Pharmaceutical Ingredients (APIs) and advanced intermediates, serving both nnovator and generic pharmaceutical companies worldwide. - Show More
Tianish Laboratories Private Limited is an Indian pharmaceutical company, incorporated on March 25, 2023, and headquartered at Jubilee Hills, Hyderabad, Telangana. The company is classified as a private, unlisted, non-government entity. Tianish Laboratories specializes in the man facture and supply of high-quality pharmaceutical raw materials, intermediates, and active pharmaceutical ingredients (APIs). Tianish Laboratories was established following the demerger of the API business from Mylan Laboratories Limited, effective March 1, 2024. The company operates multiple manufacturing units (such as Unit-8 and Unit-10) that have been inspected by major international regulatory agencies, including the USFDA, EMA, WHO, and others. These facilities produce intermediates and APIs for both domestic and international markets. - Show More
Teva Pharmaceutical Industries Ltd. is an Israeli multinational pharmaceutical company headquartered in Tel Aviv, Israel. It is the largest generic drug manufacturer in the world and ranks as the 26th largest pharmaceutical company globally. Teva specializes in generic medicines, branded drugs, and active pharmaceutical ingredients (APIs). Its notable branded products include Austedo (for Huntington's disease and tardive dyskinesia) and Ajovy (for migraine prevention), among others. - Show More
Sun Pharmaceutical Industries Limited is a leading global pharmaceutical company with a significant presence in the development, manufacturing, and marketing of Active Pharmaceutical Ingredients (APIs). The company began its API production in 1995 to support vertical integration nd facilitate the manufacture of complex formulations. Today, Sun Pharma manufactures APIs at 14 facilities across India, Hungary, the US, Israel, and Australia. - Show More
Medichem S.A. is a leading, privately held European pharmaceutical company specializing in the development and manufacture of active pharmaceutical ingredients (APIs) and finished dosage forms (FDFs) for the global generics industry. Founded in 1972 and headquartered in Sant Joan Despí, Barcelona, Spain, Medichem is recognized for its vertically integrated operations, high standards of quality, and global reach. - Show More
