3-iodo-1H-pyrazolo(3,4-d)pyrimidin-4-amine (CAS No: 151266-23-8) is a key pharmaceutical intermediate used in the synthesis of APIs Ibrutinib. This compound serves as an essential raw material in API development and synthesis. Explore detailed chemical properties, molecular data, structure information, and verified global suppliers, manufacturers, and distributors of this API intermediate on apicule.
Alternate Names: 1H-Pyrazolo[3,4-d]pyrimidin-4-amine, 3-iodo-, 4-Amino-3-iodo-1H-pyrazolo[3,4-d]pyrimidine
CAS No: 151266-23-8
PubChem CID: 1519489
Mol Formula: C5H4IN5
Mol Weight: 261.02 g/mol
Used in API: Ibrutinib
IUPAC Name: 3-iodo-2H-pyrazolo[3,4-d]pyrimidin-4-amine
API Intermediate Description: 3-Iodo-1H-pyrazolo[4-d]pyrimidin-4-amine is a key heterocyclic intermediate used to synthesize the BTK inhibitor Ibrutinib. It serves as a scaffolding agent, allowing for the Suzuki coupling of the 4-phenoxyphenyl group at the 3-position, followed by attachment of the piperidine ring at the 1-position and final acrylation to produce Ibrutinib.
