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Alternate Names: allisartan, Angizaar
CAS No: 114798-26-4
PubChem CID: 3961
Mol Formula: C22H23ClN6O
Mol Weight: 422.90 g/mol
IUPAC Name: [2-butyl-5-chloro-3-[[4-[2-(2H-tetrazol-5-yl)phenyl]phenyl]methyl]imidazol-4-yl]methanol
Therapeutic use: Antihypertensives, Cardiovascular
Drug Class: Angiotensin II Receptor Blockers (ARBs)
Commercial / Development Status: Commercial APIs
Source / Manufacturing Origin: Synthetic APIs
API Description: Losartan is a biphenylyltetrazole where a 1,1'-biphenyl group is attached at the 5-position and has an additional trisubstituted imidazol-1-ylmethyl group at the 4'-position It has a role as an antihypertensive agent, an angiotensin receptor antagonist, an endothelin receptor antagonist and an anti-arrhythmia drug. It is a biphenylyltetrazole and a member of imidazoles. It is a conjugate acid of a losartan(1-).
