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Alternate Names: G1T28 dihydrochloride dihydrate, Cosela dihydrochloride dihydrate
CAS No: 2519335-12-5
PubChem CID: 155491232
Mol Formula: C24H36Cl2N8O3
Mol Weight: 555.5 g/mol
IUPAC Name: 4-[[5-(4-methylpiperazin-1-yl)-2-pyridinyl]amino]spiro[1,3,5,11-tetrazatricyclo[7.4.0.02,7]trideca-2,4,6,8-tetraene-13,1′-cyclohexane]-10-one;di -Show More
Drug Class: CDK4/6 Inhibitors
Commercial / Development Status: Commercial APIs
API Description: Trilaciclib dihydrochloride dihydrate is used to reduce the risk of chemotherapy-induced myelosuppression in patients with extensive-stage small cell lung cancer (ES-SCLC). It acts as a CDK4/6 inhibitor, temporarily arresting bone marrow cells in the G1 phase to protect them from chemotherapy damage. This helps decrease the incidence of neutropenia, anemia, and thrombocytopenia during chemotherapy treatment.
