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Alternate Names: Sacubitril-Valsartan Trisodium Salt, Sacubitril-Valsartan Trisodium Salt 2.5hydrate
CAS No: 1898188-76-5
PubChem CID: 131801102
Mol Formula: C48H55N6Na3O8
Mol Weight: 913.0 g/mol
IUPAC Name: trisodium;4-[[(2S,4R)-5-ethoxy-4-methyl-5-oxo-1-(4-phenylphenyl)pentan-2-yl]amino]-4-oxobutanoate;(2S)-3-methyl-2-[pentanoyl-[[4-[2-(1,2,3-triaza-4-az -Show More
API Description: Sacubitril valsartan sodium anhydrous is the anhydrous (water-free) form of the combination drug used to treat heart failure with reduced ejection fraction (HFrEF). It combines sacubitril, a neprilysin inhibitor that enhances natriuretic peptides for vasodilation and fluid balance, with valsartan, an angiotensin II receptor blocker (ARB) that reduces blood pressure and cardiac strain. The anhydrous form is used in pharmaceutical formulations where precise dosing and stability are critical. This combination improves heart function, reduces hospitalizations, and lowers the risk of cardiovascular death, and is marketed under the brand name Entresto.
