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Alternate Names: Onkotrone, Mitroxone, Neotalem, Pralifan, Novantrone
CAS No: 70476-82-3
PubChem CID: 51082
Mol Formula: C22H30Cl2N4O6
Mol Weight: 517.4 g/mol
IUPAC Name: 1,4-dihydroxy-5,8-bis[2-(2-hydroxyethylamino)ethylamino]anthracene-9,10-dione;dihydrochloride
API Description: Mitoxantrone Hydrochloride is the hydrochloride salt of an anthracenedione antibiotic with antineoplastic activity. Mitoxantrone intercalates into and crosslinks DNA, thereby disrupting DNA and RNA replication. This agent also binds to topoisomerase II, resulting in DNA strand breaks and inhibition of DNA repair. Mitoxantrone is less cardiotoxic compared to doxorubicin.
