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Alternate Names: Ixempra, BMS-247550, Ixempra kit, Aza-epothilone B, BMS 247550-01
CAS No: 219989-84-1
PubChem CID: 6445540
Mol Formula: C27H42N2O5S
Mol Weight: 506.7 g/mol
IUPAC Name: (1S,3S,7S,10R,11S,12S,16R)-7,11-dihydroxy-8,8,10,12,16-pentamethyl-3-[(E)-1-(2-methyl-1,3-thiazol-4-yl)prop-1-en-2-yl]-17-oxa-4-azabicyclo[14.1.0]hept -Show More
API Description: Ixabepilone is a macrocycle that is a lactam analogue of epothilone B. Binds directly to beta-tubulin subunits on microtubules, leading to suppression of microtubule dynamics. It has a role as an antineoplastic agent and a microtubule-destabilising agent. It is a member of 1,3-thiazoles, a beta-hydroxy ketone, a lactam, a macrocycle and an epoxide.
