Sulfonylureas are an established class of oral antidiabetic drugs that lower blood glucose in type 2 diabetes by stimulating pancreatic beta‑cell insulin secretion via ATP‑sensitive potassium channel blockade. Chemically, sulfonylureas contain a sulfonyl group attached to a urea (sulfonyl‑urea) motif, with variable aryl/alkyl substitutions determining potency, PK, and receptor affinity. The following is a list of Sulfonylurea APIs.
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