GLP‑2 receptor agonists (GLP‑2 RAs) are intestinotrophic peptide drugs that enhance mucosal growth, improve nutrient absorption, and reduce parenteral nutrition needs, primarily used in short bowel syndrome–associated intestinal failure and now moving into broader GI and metabolic applications. Compared with GLP‑1 RAs, they are gut‑trophic rather than anorexigenic, with emerging roles in combination incretin strategies (e.g., GLP‑1/GLP‑2 bispecifics) and potential obesity‑adjacent indications via gut barrier and anti‑inflammatory effects rather than direct weight loss. The following is a list of GLP-2 receptor agonist APIs.
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