Apicule is a pioneering platform revolutionizing the pharmaceutical supply chain by streamlining the sourcing and trading of Active Pharmaceutical Ingredients (APIs) also known as drug substances. As a trusted intermediary, we connect pharmaceutical manufacturers, research institutions, and healthcare providers with reputable API suppliers worldwide. Our comprehensive database and advanced search capabilities enable our clients to efficiently navigate the complex landscape of API procurement, ensuring access to high-quality ingredients that meet stringent regulatory standards. At Apicule, we understand that the quality of APIs directly impacts the safety and efficacy of final drug products. Therefore, we meticulously vet our network of suppliers, considering factors such as quality assurance, regulatory compliance, and supply chain resilience. By leveraging our expertise and cutting-edge technology, we empower our clients and drug product manufacturers to make informed decisions, mitigate risks, and ultimately contribute to the development of safe and effective medications for patients globally.
Patheon Pharma Services, a subsidiary of Thermo Fisher Scientific, is a leading Contract Development and Manufacturing Organization (CDMO) that provides comprehensive solutions for drug development, clinical trial logistics, and commercial manufacturing. Since its acquisition by hermo Fisher Scientific in 2017, Patheon has become a cornerstone of the company's Pharma Services division, offering end-to-end capabilities to pharmaceutical, biotech, and life sciences industries. Patheon Pharma Solutions has its headquarters located at 168 Third Avenue, Waltham, Massachusetts, USA 02451. - Show More
Jensen-Salsbery Laboratories was a pioneering American veterinary pharmaceutical company founded around 1913 by Dr. Hans Jensen, a pharmacist, and Dr. Charles E. Salsbery, a veterinarian. The company was incorporated in 1915 and quickly became known as "Jen-Sal," producing biolog cal products for animal health, such as vaccines and serums for diseases like rabies, botulism, pink eye, anthrax, hog cholera, and encephalomyelitis. - Show More
Avantor Performance Materials LLC is a leading global provider of integrated, tailored solutions for the life sciences and advanced technology industries. Founded in 1904, Avantor has a long history rooted in science and manufactures and markets high-performance chemistries and m terials worldwide. The company's offerings include ultra-high purity chemicals and reagents used in biopharmaceutical, pharmaceutical, and other scientific research and production applications. Avantor also provides customized excipients, process chromatography materials, analytical sample prep kits, lab products, and high purity silicones, serving diverse markets such as healthcare, education, advanced technology, and applied materials. Avantor expanded significantly with the acquisition of VWR in 2017, enabling it to offer a broad portfolio with over four million products and extensive global operations in more than 30 countries. The company supports customers from discovery to delivery and is a trusted partner in regulated environments. Avantor's manufacturing and research facilities are located globally, including the United States, Mexico, The Netherlands, Poland, India, Taiwan, and China. - Show More
KV Pharmaceutical Company was an American pharmaceutical manufacturer founded in 1942 and headquartered in St. Louis, Missouri. The company specialized in producing generic and non-branded pharmaceutical products, with a particular focus in later years on women’s healthcare thr ugh its subsidiary, Ther-Rx Corporation. KV operated research, manufacturing, marketing, and sales facilities, and at its peak, employed several hundred people. In 2008, the FDA shut down KV after the company was convicted of felony charges related to the production and distribution of adulterated and unapproved drugs. Its subsidiary, Ethex Corporation, pleaded guilty to two felonies for failing to report oversized prescription drug tablets and was fined over $23.4 million, with additional restitution and forfeiture penalties. KV was reapproved to manufacture drugs in 2010 after selling its Ethex subsidiary. In 2013, the company completed a Chapter 11 bankruptcy reorganization, emerging with reduced debt and new capital investment, but all existing preferred and common stock was cancelled. - Show More
Sigma Chemical Co was an American specialty chemical company that merged with Aldrich Chemical Company in 1975 to form Sigma-Aldrich. Sigma-Aldrich grew through acquisitions and diversification and became a major supplier of chemicals and laboratory equipment worldwide. In 2015, t was acquired by the multinational Merck Group and operates as part of Merck's life sciences business under the brand MilliporeSigma. - Show More
Ben Venue Laboratories, Inc. (Ben Venue) of Bedford, Ohio, has decided to cease production by the end of 2013. Despite the ongoing support of the U.S. Food and Drug Administration (FDA), the tremendous dedication of employees, and significant investments in facility upgrades, the company cannot return to sustainable production. Although interim controls implemented to assure product quality have been effective to date, in the ...Ben Venue Laboratories, Inc. (Ben Venue) of Bedford, Ohio, has decided to cease production by the end of 2013. Despite the ongoing support of the U.S. Food and Drug Administration (FDA), the tremendous dedication of employees, and significant investments in facility upgrades, the company cannot return to sustainable production. Although interim controls implemented to assure product quality have been effective to date, in the long term, they are not sustainable. The magnitude of continued investment and time required to overcome the systemic manufacturing challenges is not viable. Given the age and condition of some of our facilities, combined with the findings from our third-party current Good Manufacturing Practice (cGMP) experts and ongoing remediation needs, Ben Venue projects, in addition to the more than $350 million invested to date, significant additional cumulative operating losses of approximately $700 million over the next five years. The effort, magnitude of investment, and additional years required to remediate the facility before Ben Venue can return to sustainable production is not feasible. Ben Venue understands the importance of the drugs the company produces, and will work to help ensure that these critical medicines continue to reach the patients who need them. The closure will affect all of Ben Venue’s employees (approximately 1,100) over a phased reduction starting this month and continuing into 2014 as Ben Venue executes wind-down activities. Boehringer Ingelheim recognizes the importance of Bedford Laboratories, Ben Venue’s generic sterile injectables business, and is exploring strategic options to try to continue the supply of these products to patients. Ben Venue has notified the FDA of this difficult decision, and is diligently working to minimize the potential impacts this decision may have on patients, providers and employees. - Show More
Chattem Chemicals, Inc. is a chemical manufacturing company based in Chattanooga, Tennessee, founded originally in 1879 as the Chattanooga Medicine Company. It produces a variety of active pharmaceutical ingredients (APIs), performance chemicals, catalysts, surfactants, and addit ves used in consumer and industrial markets worldwide. Their products serve sectors including pharmaceuticals, health and beauty, industrial applications like inks and paints, and more. Chattem Chemicals is known for manufacturing controlled substances in pharmaceuticals as well as specialty chemicals such as glycine and sarcosinate surfactants. The company operates a state-of-the-art generic API manufacturing facility focusing on integrity, safety, and security. It has historically been part of the larger Chattem, Inc., which was acquired by Sanofi, and currently is a subsidiary of Sun Pharmaceuticals. - Show More
Actavis plc (NYSE: ACT) is a unique specialty pharmaceutical company focused on developing, manufacturing and commercializing high quality affordable generic and innovative branded pharmaceutical products for patients around the world. The Company has global headquarters in Dubl n, Ireland and U.S. Administrative Headquarters in Parsippany, New Jersey, USA. Highlights Actavis markets a broad portfolio of branded and gene...Actavis plc (NYSE: ACT) is a unique specialty pharmaceutical company focused on developing, manufacturing and commercializing high quality affordable generic and innovative branded pharmaceutical products for patients around the world. The Company has global headquarters in Dublin, Ireland and U.S. Administrative Headquarters in Parsippany, New Jersey, USA. Highlights Actavis markets a broad portfolio of branded and generic pharmaceuticals and develops innovative medicines for patients suffering from diseases principally in the central nervous system, gastroenterology, women’s health, urology, cardiovascular, respiratory and anti-infective therapeutic categories. Actavis markets approximately 1000 generic, branded generic, established brands and Over-the-Counter (OTC) pharmaceutical products globally through operations in more than 60 countries. The Company is an industry leader in product research and development, with one of the broadest brand development pipelines in the pharmaceutical industry, and a leading position in the submission of generic product applications. Actavis has commercial operations in more than 60 countries and operates more than 30 manufacturing and distribution facilities around the world. - Show More
Incorporated by Edwin R. Thompson in September, 1994, Pharmaceutical Manufacturing Research Services (PMRS, Inc.) has grown into a world-class supplier of pharmaceutical services. A privately held company still under Thompson's ownership, we constantly strive to surpass industry tandards. We invest in the long term, investing in the brightest minds, the most advanced technology, and a state-of-the-art facility. Our commitment...Incorporated by Edwin R. Thompson in September, 1994, Pharmaceutical Manufacturing Research Services (PMRS, Inc.) has grown into a world-class supplier of pharmaceutical services. A privately held company still under Thompson's ownership, we constantly strive to surpass industry standards. We invest in the long term, investing in the brightest minds, the most advanced technology, and a state-of-the-art facility. Our commitment to efficiency has enabled us to produce superior pharmaceuticals for the lowest possible cost. - Show More
Veranova, L.P. is a global contract development and manufacturing organization (CDMO) that specializes in the development and manufacturing of complex and specialist active pharmaceutical ingredients (APIs). The company was formerly known as Johnson Matthey Health before being ac uired and rebranded in 2022. - Show More