Apicule is a pioneering platform revolutionizing the pharmaceutical supply chain by streamlining the sourcing and trading of Active Pharmaceutical Ingredients (APIs) also known as drug substances. As a trusted intermediary, we connect pharmaceutical manufacturers, research institutions, and healthcare providers with reputable API suppliers worldwide. Our comprehensive database and advanced search capabilities enable our clients to efficiently navigate the complex landscape of API procurement, ensuring access to high-quality ingredients that meet stringent regulatory standards. At Apicule, we understand that the quality of APIs directly impacts the safety and efficacy of final drug products. Therefore, we meticulously vet our network of suppliers, considering factors such as quality assurance, regulatory compliance, and supply chain resilience. By leveraging our expertise and cutting-edge technology, we empower our clients and drug product manufacturers to make informed decisions, mitigate risks, and ultimately contribute to the development of safe and effective medications for patients globally.
FIS Fabbrica Italiana Sintetici SpA (FIS) is a private Italian company specializing in the development and production of active pharmaceutical ingredients (APIs) for the pharmaceutical industry. Founded in 1957, it operates with more than 1,850 employees and has three production ites in Italy, including Montecchio Maggiore and Termoli. The company has over 60 years of experience and is known for its strong focus on research & development (R&D), innovation, and quality management systems. FIS produces a wide range of APIs, including those for anti-cancer treatments, steroids, psychotropics, antibiotics (non-beta lactams), antibacterials, anti-inflammatory drugs, diuretics, and veterinary APIs. Their manufacturing capabilities cover commercial production with dedicated or multi-purpose lines, including sterile manufacturing, micronization, lyophilization, and spray drying technologies. - Show More
Euticals S.p.A. is a prominent company in the pharmaceutical and fine chemicals industry, established in 1984 and headquartered in Lodi, Italy. The company specializes in the production of active pharmaceutical ingredients (APIs), custom synthesis, and fine chemicals for both the pharmaceutical and nutritional industries. Euticals operates globally, with manufacturing sites in Italy, France, Germany, and the USA, all of which are regularly inspected by international regulatory agencies such as the FDA, KFDA, and ANVISA. - Show More
Farmabios SpA is a leading Italian manufacturer of active pharmaceutical ingredients (APIs), specializing in steroids, hormones, and high-potency compounds. Founded in 1968 and headquartered in Gropello Cairoli, near Milan, Farmabios is now part of the Axplora Group, a major Euro ean API manufacturing network. - Show More
Ibi was founded in 1918 by Professor Giovanni Lorenzini. A long tradition in the field of scientific research together with the innovative technologies applied and the level of care and attention to production have given Ibi its reputation for reliability and high quality. The Ib plant covers an area of 18,000 square metres, on which a new building is entirely dedicated to the production of ß-lactamics. Offering state of the...Ibi was founded in 1918 by Professor Giovanni Lorenzini. A long tradition in the field of scientific research together with the innovative technologies applied and the level of care and attention to production have given Ibi its reputation for reliability and high quality. The Ibi plant covers an area of 18,000 square metres, on which a new building is entirely dedicated to the production of ß-lactamics. Offering state of the art service and technology, Ibi is among the top ten Italian companies in toll manufacturing. Today Ibi is present in over 30 countries, exporting two thirds of its total production. It is one of few companies not producing in the United States that has obtained FDA approval for the production of sterile penicillin for the American market. Ibi has developed a new distribution strategy directly to hospitals, entrusting the sales of its products to a special new organization, Ibisqus, created in joint venture and present in the UK, Germany and Italy. Ibi is present on the Italian market with a variety of products ranging from sterile penicillin to food supplements. It is well known for the reputation of its products in the area of antinfective therapy and gastroenterology. A network of highly qualified scientific informers enables Ibi to contact the universe of gastroenterologist specialist and 55% of infectious disase specialist. Ibi provides directly 4000 pharmacies. In addition to its tradition and quality, today Ibi is proud of its innovative laboratories and expert researchers, able to offer new services in the fields of Biotechnology and Nano-medicine, especially in the development of processes for the production of recombinant proteins in cGMP and in the planning and production of new delivery systems. Years of experience in formulation studies, in the development of production processes and in industrial scale-up enable Ibi to face the new challenges on the pharmaceutical market with confidence. Ibi produces its products in conformity with the regulations of the European Pharmacopoeia and the cGMP norms. It is, in addition, certified by the most demanding Health Authorities: AIFA, FDA, TGA and MCA. - Show More
Sicor de Mexico, located near Toluca, Mexico, specializes in the production of highly potent active pharmaceutical ingredients. This is a highly specialized facility with expertise in the production of high volume steroids, steroidal cancer products and platinum derived cancer co pounds. The API’s produced at this facility are primarily used in injectable, inhalation, nasal and topical formulations. | Sicor’s plants provide a global platform for the manufacture and marketing of APIs for injectable, inhalation, topical and nasal products. These specialized plants possess a high level of expertise in the production of steroids, hormones and cytotoxic products. Sicor produces about 60 active ingredients and offers one of the widest ranges of anti-cancer drugs on the market today. | Sicor, five letters, a unique story going through the decades and travelling towards the future. It was 1981, in fact, when the ambitious project became tangible matter: what had previously been imagined on paper, became a real business! A company thought of in a different way, set up in a strategic territory: head-quartered in Rovereto, in the north-eastern Italian province of Trento, sheltered by the Alps, located within a...Sicor, five letters, a unique story going through the decades and travelling towards the future. It was 1981, in fact, when the ambitious project became tangible matter: what had previously been imagined on paper, became a real business! A company thought of in a different way, set up in a strategic territory: head-quartered in Rovereto, in the north-eastern Italian province of Trento, sheltered by the Alps, located within a few dozen miles away from the Austrian border…..an Italian brand with sheer determination to succeed abroad. - Show More
TRIFARMA S.p.A. is an international and independent Group with the Mission to develop, manufacture and supply worldwide high quality APIs (Active Pharmaceutical Ingredients) to the global pharmaceutical industry. In order to further improve its presence on the globalized pharmace tical marketplace, the two Italian API factories (formerly named Alchymars SpA and ICM Industria Chimica Milanese SpA) have merged into TRIFARMA SpA,...TRIFARMA S.p.A. is an international and independent Group with the Mission to develop, manufacture and supply worldwide high quality APIs (Active Pharmaceutical Ingredients) to the global pharmaceutical industry. In order to further improve its presence on the globalized pharmaceutical marketplace, the two Italian API factories (formerly named Alchymars SpA and ICM Industria Chimica Milanese SpA) have merged into TRIFARMA SpA, thus creating a larger and industrially, commercially stronger organization. The Shareholders of Trifarma also control the Indian company Alchymars ICM SM Pvt Ltd (abbreviated as AIS) located in Chennai, India. - Show More
Indena S.p.A. is a globally recognized Italian company specializing in the identification, development, and production of high-quality active principles derived from plants. These botanical extracts and purified compounds are used primarily in the pharmaceutical, health-food (nut aceutical), and cosmetics industries. - Show More
