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Alternate Names: Vocinti, Takecab
CAS No: 881681-00-1
PubChem CID: 15981397
Mol Formula: C17H16FN3O2S
Mol Weight: 345.4 g/mol
IUPAC Name: 1-[5-(2-fluorophenyl)-1-pyridin-3-ylsulfonylpyrrol-3-yl]-N-methylmethanamine
Commercial / Development Status: Commercial APIs
Source / Manufacturing Origin: Synthetic APIs
API Description: Vonoprazan is a potassium-competitive acid blocker, with acid suppressing activity. Upon oral administration, vonoprazan concentrates in the gastric parietal cells and competitively and reversibly binds to the potassium binding site of the proton pump hydrogen-potassium adenosine triphosphatase (H+/K+ ATPase), thereby inhibiting the pump's activity and the parietal cell secretion of H+ ions into the gastric lumen, the final step in gastric acid production.
