Find verified Trimethoprim lactate API manufacturers, suppliers, and distributors across the globe. Explore companies that offer high-purity Trimethoprim lactate for pharmaceutical use, along with product details, certifications, and reliable sourcing options. Compare prices, check availability, and connect directly with trusted suppliers for Trimethoprim lactate API.
Alternate Names: Trimethoprim lactate salt, Trimethoprim lactic Acid, Wellcoprim (TN)
CAS No: 23256-42-0
PubChem CID: 3084396
Mol Formula: C17H24N4O6
Mol Weight: 380.4 g/mol
IUPAC Name: 2-hydroxypropanoic acid;5-[(3,4,5-trimethoxyphenyl)methyl]pyrimidine-2,4-diamine
Alternate Use: API Intermediate
Commercial / Development Status: Commercial APIs
Source / Manufacturing Origin: Synthetic APIs
API Description: Trimethoprim lactate is a synthetic derivative of trimethoprim, used as a bacteriostatic antibiotic with activity against a wide range of Gram-positive and Gram-negative aerobic bacteria. It works by inhibiting bacterial dihydrofolate reductase, which blocks the conversion of dihydrofolic acid to tetrahydrofolic acid, an essential precursor in bacterial folic acid synthesis. This inhibition disrupts DNA synthesis and bacterial growth. Trimethoprim lactate is commonly combined with sulfonamides (e.g., sulfamethoxazole) to produce bactericidal effects, though it is only bacteriostatic on its own. It is effective against bacteria involved in urinary tract infections, mild acute prostatitis, cystitis, and some protozoal infections.
