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Alternate Names: Ralivia flashtab, Tramaliv,Tramadol Contramid
CAS No: 123154-38-1
PubChem CID: 33741
Mol Formula: C16H25NO2
Mol Weight: 263.37 g/mol
IUPAC Name: (1R,2R)-2-[(dimethylamino)methyl]-1-(3-methoxyphenyl)cyclohexan-1-ol
API Description: Tramadol is a synthetic, centrally acting opioid analgesic used to treat moderate to moderately severe pain. It produces analgesia through a dual mechanism of action: weak agonism at μ-opioid receptors and inhibition of serotonin and norepinephrine reuptake in the central nervous system. This combination reduces pain transmission and enhances descending inhibitory pain pathways.After oral administration, tramadol is well absorbed and undergoes hepatic metabolism, primarily via CYP2D6, to form an active metabolite (O-desmethyltramadol) with stronger opioid activity. It is eliminated mainly through the kidneys. Because of genetic variability in metabolism, its effects can be unpredictable, ranging from poor pain relief to increased risk of toxicity.
