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Alternate Names: 1,8-Naphthyridine-3-carboxylic acid, 7-(3-amino-1-pyrrolidinyl)-1-(2,4-difluorophenyl)-6-fluoro-1,4-dihydro-4-oxo-, 4-methylbenzenesulfonate, Tosufloxacin toluenesulfonate
CAS No: 100490-94-6
PubChem CID: 93858
Mol Formula: C26H23F3N4O6S
Mol Weight: 576.5 g/mol
IUPAC Name: 7-(3-aminopyrrolidin-1-yl)-1-(2,4-difluorophenyl)-6-fluoro-4-oxo-1,8-naphthyridine-3-carboxylic acid;4-methylbenzenesulfonic acid
Drug Class: Fluoroquinolones, Topoisomerase inhibitors
Commercial / Development Status: Commercial APIs
Source / Manufacturing Origin: Synthetic APIs
API Description: Tosufloxacin Tosylate is a synthetic fluoroquinolone antibiotic API used in pharmaceutical formulations for the treatment of bacterial infections. It is the tosylate salt form of tosufloxacin, designed to improve the compound’s solubility, stability, and formulation properties.Pharmacologically, tosufloxacin exhibits broad-spectrum antibacterial activity against both Gram-positive and Gram-negative bacteria. It works by inhibiting bacterial DNA gyrase (topoisomerase II) and topoisomerase IV, enzymes essential for DNA replication, transcription, and repair. This results in bactericidal action, meaning it actively kills bacteria rather than just inhibiting growth.
