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Alternate Names: RP6530, tenalisibum, (S)-2-(1-((9H-Purin-6-yl)amino)propyl)-3-(3-fluorophenyl)-4H-chromen-4-one
CAS No: 1639417-53-0
PubChem CID: 86291103
Mol Formula: C23H18FN5O2
Mol Weight: 415.4 g/mol
IUPAC Name: 3-(3-fluorophenyl)-2-[(1S)-1-(7H-purin-6-ylamino)propyl]chromen-4-one
API Description: Tenalisib is a drug under investigation for treating relapsed/refractory lymphoid malignancies, particularly T-cell lymphomas, and has shown potential in breast cancer and other hematologic cancers. It works by inhibiting the phosphoinositide 3-kinase delta and gamma (PI3Kδ/γ) and salt-inducible kinase 3 (SIK3), which reduces tumor cell proliferation, induces apoptosis (programmed cell death), and modulates the tumor microenvironment.