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Alternate Names: 4-Thia-1-azabicyclo(3.2.0)heptane-2-carboxylic acid, 3-methyl-7-oxo-3-(1H-1,2,3-triazol-1-ylmethyl)-, 4,4-dioxide, hydrate (2:1), (2S,3S,5R)-, Tazobactam hydrate
CAS No: 428863-55-2
PubChem CID: 133082183
Mol Formula: C20H26N8O11S2
Mol Weight: 618.6 g/mol
IUPAC Name: (2S,3S,5R)-3-methyl-4,4,7-trioxo-3-(triazol-1-ylmethyl)-4λ6-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid;hydrate
Drug Class: Sulfones
Commercial / Development Status: Commercial APIs
Source / Manufacturing Origin: Synthetic APIs
API Description: Tazobactam hemihydrate is primarily used as a β-lactamase inhibitor in combination with β-lactam antibiotics, especially piperacillin, to treat bacterial infections. The hemihydrate form refers to its crystalline structure containing half a molecule of water per molecule of tazobactam, which influences its stability and formulation, but not its pharmacological activity.
