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Alternate Names: Tacrolimus hydrate, Tsukubaenolide hydrate, Prograf (TN)
CAS No: 109581-93-3
PubChem CID: 5282315
Mol Formula: C44H71NO13
Mol Weight: 822.0 g/mol
IUPAC Name: (1R,9S,12S,13R,14S,17R,18E,21S,23S,24R,25S,27R)-1,14-dihydroxy-12-[(E)-1-[(1R,3R,4R)-4-hydroxy-3-methoxycyclohexyl]prop-1-en-2-yl]-23,25-dimethoxy-13, -Show More
Therapeutic use: Anti-psoriatic agents, Antirheumatic Agents, Dermatologicals
Drug Class: Calcineurin inhibitors, Immunosuppressants
Commercial / Development Status: Commercial APIs
Source / Manufacturing Origin: Fermentation-derived APIs
API Description: Tacrolimus Hydrate is used topically to treat inflammatory skin conditions like atopic dermatitis (eczema) and psoriasis by suppressing the immune system's response in the skin. It is also used systemically, often in conjunction with other medications, to prevent the rejection of transplanted organs, such as kidneys, liver, lungs, and hearts, by decreasing overall immune system activity.
