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Alternate Names: Scopine HCl, Scopine (hydrochloride)
CAS No: 85700-55-6
PubChem CID: 24720972
Mol Formula: C8H14ClNO2
Mol Weight: 191.65 g/mol
IUPAC Name: (1S,2S,4R,5R)-9-methyl-3-oxa-9-azatricyclo[3.3.1.02,4]nonan-7-ol;hydrochloride
API Description: Scopine hydrochloride is a scopolamine metabolite notable for its selective binding to muscarinic receptors (IC₅₀ ≈ 3 µM). In research, it's been utilized as a brain-targeting delivery vector, enhancing chlorambucil’s ability to cross the blood–brain barrier and improve antitumor activity in glioma models. Additionally, it demonstrates behavioral modulatory effects in model organisms and is important as a synthetic intermediate in manufacturing tiotropium bromide. Some references also suggest it might act as an α₁‑adrenergic agonist in circulatory shock contexts, although this application is less substantiated.
