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Alternate Names: Jakafi, Jakavi, 5BC7RM522L
CAS No: 2927441-77-6
PubChem CID: 171390136
Mol Formula: C18H22N6O3S
Mol Weight: 402.5 g/mol
IUPAC Name: (3R)-3-cyclopentyl-3-[4-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)pyrazol-1-yl]propanenitrile;methanesulfonic acid
API Description: Ruxolitinib mesylate is a salt form of Ruxolitinib, a JAK1/JAK2 inhibitor used to treat various hematologic and inflammatory conditions. Used to treat myelofibrosis, a rare bone marrow cancer. Indicated for polycythemia vera, especially in patients intolerant to hydroxyurea. Approved for acute and chronic graft-versus-host disease (GVHD). Investigated for autoimmune and inflammatory diseases, like atopic dermatitis and alopecia areata.
