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Alternate Names: Jakafi, Jakavi
CAS No: 1912373-07-9
PubChem CID: 169490818
Mol Formula: C17H19ClN6
Mol Weight: 342.8 g/mol
IUPAC Name: (3R)-3-cyclopentyl-3-[4-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)pyrazol-1-yl]propanenitrile;hydrochloride
API Description: Ruxolitinib hydrochloride is a salt form of Ruxolitinib, a JAK1/JAK2 inhibitor used to treat certain blood cancers and inflammatory conditions. Treats myelofibrosis and polycythemia vera, both rare blood disorders. Approved for acute and chronic graft-versus-host disease (GVHD). Investigated for autoimmune diseases like alopecia areata and atopic dermatitis. Works by inhibiting JAK-STAT signaling, reducing inflammation and abnormal cell growth.
