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Alternate Names: 9-Nitrocamptothecin, Orathecin
CAS No: 91421-42-0
PubChem CID: 472335
Mol Formula: C20H15N3O6
Mol Weight: 393.3 g/mol
IUPAC Name: (19S)-19-ethyl-19-hydroxy-8-nitro-17-oxa-3,13-diazapentacyclo[11.8.0.02,11.04,9.015,20]henicosa-1(21),2,4(9),5,7,10 -Show More
Commercial / Development Status: Discontinued APIs
Source / Manufacturing Origin: Semi-synthetic APIs
API Description: Rubitecan is a pyranoindolizinoquinoline that is camptothecin in which the hydrogen at position 9 has been replaced by a nitro group. It is a prodrug for 9-aminocamptothecin. It has a role as an antineoplastic agent, an EC 5.99.1.2 (DNA topoisomerase) inhibitor and a prodrug. It is a pyranoindolizinoquinoline, a C-nitro compound, a semisynthetic derivative, a tertiary alcohol and a delta-lactone.
