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Alternate Names: FG-4592, roxadustatum, Evrenzo (TN)
CAS No: 808118-40-3
PubChem CID: 11256664
Mol Formula: C19H16N2O5
Mol Weight: 352.3 g/mol
IUPAC Name: 2-[(4-hydroxy-1-methyl-7-phenoxyisoquinoline-3-carbonyl)amino]acetic acid
API Description: Roxadustat is a first-in-class hypoxia-inducible factor prolyl hydroxylase inhibitor used to treat anemia associated with chronic kidney disease. It works by reducing the breakdown of the hypoxia-inducible factor (HIF), which is a transcription factor that stimulates red blood cell production in response to low oxygen levels. Roxadustat was first approved by the European Commission in August 2021.
