Find verified Rizatriptan benzoate API manufacturers, suppliers, and distributors across the globe. Explore companies that offer high-purity Rizatriptan benzoate for pharmaceutical use, along with product details, certifications, and reliable sourcing options. Compare prices, check availability, and connect directly with trusted suppliers for Rizatriptan benzoate API.
Alternate Names: Maxalt-MLT, RIZAFILM, L 705126
CAS No: 145202-66-0
PubChem CID: 77997
Mol Formula: C22H25N5O2
Mol Weight: 391.5 g/mol
IUPAC Name: benzoic acid;N,N-dimethyl-2-[5-(1,2,4-triazol-1-ylmethyl)-1H-indol-3-yl]ethanamine
API Description: Rizatriptan Benzoate is the benzoate salt form of rizatriptan, a member of the triptan class agents with anti-migraine property. Rizatriptan benzoate selectively binds to and activates serotonin (5-HT) 1B receptors expressed in intracranial arteries, and to 5-HT 1D receptors located on peripheral trigeminal sensory nerve terminals in the meninges and central terminals in brain stem sensory nuclei. Receptor binding results in constriction of cranial vessels and inhibition of nociceptive transmission, thereby providing relief of migraine headaches. Rizatriptan benzoate may also relief migraine headaches by inhibition of pro-inflammatory neuropeptide release.
