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Alternate Names: relebactamum, (1R,2S,5R)-7-oxo-2-(piperidin-4-ylcarbamoyl)-1,6-diazabicyclo[3.2.1]octan-6-yl hydrogen sulfate
CAS No: 1174018-99-5
PubChem CID: 44129647
Mol Formula: C12H20N4O6S
Mol Weight: 348.38 g/mol
IUPAC Name: [(2S,5R)-7-oxo-2-(piperidin-4-ylcarbamoyl)-1,6-diazabicyclo[3.2.1]octan-6-yl] hydrogen sulfate
API Description: Relebactam is used as part of a combination antibiotic (with imipenem/cilastatin) to treat serious bacterial infections, especially those caused by multidrug-resistant (MDR) Gram-negative bacteria, including complicated urinary tract infections (cUTIs), complicated intra-abdominal infections (cIAIs), and hospital-acquired/ventilator-associated pneumonia (HABP/VABP). It works by protecting imipenem from bacterial enzymes (beta-lactamases), restoring its ability to kill resistant bacteria like Pseudomonas aeruginosa and carbapenem-resistant Enterobacterales (CRE).
