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Alternate Names: Pemetrexed dipotassium salt
CAS No: 1438895-00-1
PubChem CID: 136266586
Mol Formula: C20H19K2N5O6
Mol Weight: 503.6 g/mol
IUPAC Name: dipotassium;(2S)-2-[[4-[2-(2-amino-4-oxo-3,7-dihydropyrrolo[2,3-d]pyrimidin-5-yl)ethyl]benzoyl]amino]pentanedioate
API Description: Pemetrexed dipotassium is a chemotherapy drug used primarily to treat certain cancers such as non-small cell lung cancer and malignant pleural mesothelioma. It is a folate analog metabolic inhibitor that disrupts folate-dependent processes essential for cancer cell replication by inhibiting enzymes like thymidylate synthase, dihydrofolate reductase, and glycinamide ribonucleotide formyltransferase, thereby impeding DNA and RNA synthesis in cancer cells.
