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Alternate Names: Axtle (TN), L-Glutamic acid, N-[4-[2-(2-amino-4,7-dihydro-4-oxo-3H-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl]benzoyl]-, potassium salt, hydrate (1:2:7)
CAS No: 2668267-29-4
PubChem CID: 136238656
Mol Formula: C20H33K2N5O13
Mol Weight: 629.7 g/mol
IUPAC Name: dipotassium;(2S)-2-[[4-[2-(2-amino-4-oxo-3,7-dihydropyrrolo[2,3-d]pyrimidin-5-yl)ethyl]benzoyl]amino]pentanedioate;heptahydrate
API Description: Pemetrexed dipotassium heptahydrate is a chemotherapy drug used primarily to treat malignant pleural mesothelioma and non-squamous non-small cell lung cancer (NSCLC). It works as a folate analog metabolic inhibitor, disrupting folate-dependent processes essential for cell replication by inhibiting enzymes involved in the biosynthesis of thymidine and purine nucleotides.
