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Alternate Names: Albamycin, Albadry, Cathomycin, Cathomycin sodium
CAS No: 1476-53-5
PubChem CID: 23663939
Mol Formula: C31H35N2NaO11
Mol Weight: 634.6 g/mol
IUPAC Name: sodium;7-[(2R,3R,4S,5R)-4-carbamoyloxy-3-hydroxy-5-methoxy-6,6-dimethyloxan-2-yl]oxy-3-[[4-hydroxy-3-(3-methylbut-2-enyl)benzoyl]amino]-8-methyl-2-oxo -Show More
API Description: Novobiocin sodium is an antibiotic primarily used in laboratory research rather than clinical treatment. It works by inhibiting bacterial DNA gyrase, an enzyme essential for DNA replication, making it effective against certain Gram-positive bacteria. In microbiology, it is commonly used to differentiate coagulase-negative staphylococci, especially in identifying Staphylococcus saprophyticus, which is resistant to novobiocin, from Staphylococcus epidermidis, which is sensitive. Its clinical use is limited due to toxicity and the availability of safer alternatives.