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Alternate Names: 1H-Indole-6-carboxylic acid, 2,3-dihydro-3-(((4-(methyl(2-(4-methyl-1-piperazinyl)acetyl)amino)phenyl)amino)phenylmethylene)-2-oxo-, methyl ester, (3Z)-, methanesulfonate, hydrate (2:2:1)
CAS No: 959762-24-4
PubChem CID: 162625094
Mol Formula: C66H80N10O15S2
Mol Weight: 1317.5 g/mol
IUPAC Name: ethanesulfonic acid;methyl 2-hydroxy-3-[N-[4-[methyl-[2-(4-methylpiperazin-1-yl)acetyl]amino]phenyl]-C-phenylcarbonimidoyl]-1H-indole-6-carboxylate;hy -Show More
API Description: Nintedanib esylate hemihydrate is a medication primarily used to treat idiopathic pulmonary fibrosis (IPF), a condition that causes progressive scarring of the lungs. It is also used in certain cases of chronic fibrosing interstitial lung diseases and systemic sclerosis-associated interstitial lung disease. Nintedanib works as a tyrosine kinase inhibitor, targeting multiple pathways involved in fibrosis and inflammation, thereby slowing the progression of lung damage.