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Alternate Names: nilotinibum, 4-Methyl-3-((4-(3-pyridinyl)-2-pyrimidinyl)amino)-N-(5-(4-methyl-1H-imidazol-1-yl)-3-(trifluoromethyl)phenyl)benzamide
CAS No: 641571-10-0
PubChem CID: 644241
Mol Formula: C28H22F3N7O
Mol Weight: 529.5 g/mol
IUPAC Name: 4-methyl-N-[3-(4-methylimidazol-1-yl)-5-(trifluoromethyl)phenyl]-3-[(4-pyridin-3-ylpyrimidin-2-yl)amino]benzamide
API Description: Nilotinib is a targeted anticancer drug used primarily to treat chronic myeloid leukemia (CML). It is a tyrosine kinase inhibitor (TKI) that specifically blocks the BCR-ABL protein, an abnormal enzyme produced by the Philadelphia chromosome mutation found in CML patients. By inhibiting this enzyme, nilotinib helps stop the uncontrolled growth of cancerous white blood cells. It is typically used in patients who are newly diagnosed or who are resistant or intolerant to earlier treatments like imatinib.