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Alternate Names: Neratinib maleate monohydrate, 1144516-12-0, 2-Butenamide, N-(4-((3-chloro-4-(2-pyridinylmethoxy)phenyl)amino)-3-cyano-7-ethoxy-6-quinolinyl)-4-(dimethylamino)-, (2E)-, (2Z)-2-butenedioate, hydrate (1:1:1)
CAS No: 1144516-12-0
PubChem CID: 25267298
Mol Formula: C34H35ClN6O8
Mol Weight: 691.1 g/mol
IUPAC Name: (Z)-but-2-enedioic acid;(E)-N-[4-[3-chloro-4-(pyridin-2-ylmethoxy)anilino]-3-cyano-7-ethoxyquinolin-6-yl]-4-(dimethylamino)but-2-enamide;hydrate
API Description: Neratinib maleate monohydrate is an oral cancer medication used for the extended adjuvant treatment of early-stage HER2-positive breast cancer after trastuzumab therapy. It works by irreversibly blocking HER1, HER2, and HER4 receptors to prevent cancer cell growth. It is taken daily with food, and common side effects include diarrhea, nausea, and fatigue.
