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Alternate Names: Nopicor, Remitch
CAS No: 152658-17-8
PubChem CID: 6918287
Mol Formula: C28H33ClN2O5
Mol Weight: 513.0 g/mol
IUPAC Name: (E)-N-[(4R,4aS,7R,7aR,12bS)-3-(cyclopropylmethyl)-4a,9-dihydroxy-1,2,4,5,6,7,7a,13-octahydro-4,12-methanobenzofuro[3,2-e]isoquinolin-7-yl]-3-(furan- -Show More
API Description: Nalfurafine hydrochloride is an anti-itch (antipruritic) drug, approved in Japan, used for severe itching (pruritus) in patients with chronic kidney disease on hemodialysis or peritoneal dialysis, and those with chronic liver disease, especially when other treatments fail. It works as a selective kappa-opioid receptor agonist, reducing itch intensity, improving sleep, and enhancing quality of life, with a lower risk of addiction compared to traditional opioids.
