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Alternate Names: Provigil, Modiodal, modaphonil, Alertec, Sparlon
CAS No: 68693-11-8
PubChem CID: 4236
Mol Formula: C15H15NO2S
Mol Weight: 273.4 g/mol
IUPAC Name: 2-benzhydrylsulfinylacetamide
API Description: Modafinil is a stimulant drug marketed as a 'wakefulness promoting agent' and is one of the stimulants used in the treatment of narcolepsy. Narcolepsy is caused by dysfunction of a family of wakefulness-promoting and sleep-suppressing peptides, the orexins, whose neurons are activated by modafinil. The prexin neuron activation is associated with psychoactivation and euphoria. The exact mechanism of action is unclear, although in vitro studies have shown it to inhibit the reuptake of dopamine by binding to the dopamine reuptake pump, and lead to an increase in extracellular dopamine. Modafinil activates glutamatergic circuits while inhibiting GABA.
