Find verified Metformin Hydrochloride API manufacturers, suppliers, and distributors across the globe. Explore companies that offer high-purity Metformin Hydrochloride for pharmaceutical use, along with product details, certifications, and reliable sourcing options. Compare prices, check availability, and connect directly with trusted suppliers for Metformin Hydrochloride API.
Alternate Names: Metformin, Metformin HCl, 1,1-Dimethylbiguanide hydrochloride
CAS No: 1115-70-4
Mol Formula: C4H12ClN5
Mol Weight: 165.62 g/mol
IUPAC Name: 3-(diaminomethylidene)-1,1-dimethylguanidine;hydrochloride
API Description: Metformin is the most popular anti-diabetic drug in the United States and one of the most prescribed drugs in the country overall, with nearly 35 million prescriptions filled in 2006 for generic metformin alone. Metformin is a biguanide antihyperglycemic agent used for treating non-insulin-dependent diabetes mellitus (NIDDM). It improves glycemic control by decreasing hepatic glucose production, decreasing glucose absorption and increasing insulin-mediated glucose uptake. Metformin is the only oral antihyperglycemic agent that is not associated with weight gain. Metformin may induce weight loss and is the drug of choice for obese NIDDM patients. When used alone, metformin does not cause hypoglycemia; however, it may potentiate the hypoglycemic effects of sulfonylureas and insulin. Its main side effects are dyspepsia, nausea and diarrhea. Dose titration and/or use of smaller divided doses may decrease side effects. Metformin should be avoided in those with severely compromised renal function (creatinine clearance < 30 ml/min), acute/decompensated heart failure, severe liver disease and for 48 hours after the use of iodinated contrast dyes due to the risk of lactic acidosis. Lower doses should be used in the elderly and those with decreased renal function. Metformin decreases fasting plasma glucose, postprandial blood glucose and glycosolated hemoglobin (HbA1c) levels, which are reflective of the last 8-10 weeks of glucose control. Metformin may also have a positive effect on lipid levels. In 2012, a combination tablet of linagliptin plus metformin hydrochloride was marketed under the name Jentadueto for use in patients when treatment with both linagliptin and metformin is appropriate.
Lupin Limited is a leading Indian multinational pharmaceutical company headquartered in Mumbai. Founded in 1968 by Dr. Desh Bandhu Gupta, Lupin has grown to become the 7th largest pharmaceutical company in India and one of the top 10 generic pharmaceutical companies globally by r venue. - Show More
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Wanbury Limited, one of India’s fastest growing pharmaceutical companies amongst the ‘Top 50 Companies’ in India (as per ORG-IMS), has a strong presence in API global market and domestic branded Formulation. Wanbury’s major trust area lies in Active Pharmaceutical Ingredi nt (API) Sales & Marketing in over 50 countries and Pan-India Formulation presence.Wanbury has a basket of over 13 API products. It is the largest ma...Wanbury Limited, one of India’s fastest growing pharmaceutical companies amongst the ‘Top 50 Companies’ in India (as per ORG-IMS), has a strong presence in API global market and domestic branded Formulation. Wanbury’s major trust area lies in Active Pharmaceutical Ingredient (API) Sales & Marketing in over 50 countries and Pan-India Formulation presence.Wanbury has a basket of over 13 API products. It is the largest manufacturer of Metformin with over 8500 tons per year. It has the larger customer base in Europe & US for Tramadol & Setraline (API) - Show More
Ningxia Hengkang Technology Co., Ltd. was founded in 2013 and is situated in Ningxia Helan Industrial Park. Encompassing an expansive area of 130,000 square meters, the company boasts a registered capital of 200 million yuan. It operates as a comprehensive enterprise, engaging in the production of guanidinium salt intermediates, pharmaceutical raw materials, animal nutrition, food health care, and new materials. Functioning as...Ningxia Hengkang Technology Co., Ltd. was founded in 2013 and is situated in Ningxia Helan Industrial Park. Encompassing an expansive area of 130,000 square meters, the company boasts a registered capital of 200 million yuan. It operates as a comprehensive enterprise, engaging in the production of guanidinium salt intermediates, pharmaceutical raw materials, animal nutrition, food health care, and new materials. Functioning as a technology-driven entity, it integrates research and development (R&D), production, and sales of a diverse range of products. - Show More
Auro Laboratories is a manufacturer of Active Pharmaceutical Ingredients (API's), Intermediates and Generic Formulations. Auro Laboratories was founded and incorporated in 1992 at Mumbai, with a manufacturing facility located at Tarapur, 120 Km from Mumbai. Since inception we hav focused on providing quality pharmaceuticals while maintaining high manufacturing standards. - Show More
