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Alternate Names: Alkeran hydrochloride, L-Phenylalanine mustard hydrochloride, Evomela
CAS No: 3223-07-2
PubChem CID: 9927978
Mol Formula: C13H19Cl3N2O2
Mol Weight: 341.7 g/mol
IUPAC Name: (2S)-2-amino-3-[4-[bis(2-chloroethyl)amino]phenyl]propanoic acid;hydrochloride
API Description: Melphalan Hydrochloride is a bifunctional alkylating agent and phenylalanine derivative of nitrogen mustard. Melphalan hydrochloride is converted into highly reactive ethylenimmonium intermediates that induce covalent guanine N7-N7 intra- and inter-crosslinks and alkylation of adenine N3 of DNA. This agent also alkylates RNA and protein structures. As a result RNA transcription and protein synthesis are inhibited, ultimately leading to cell growth arrest and/or death.