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Alternate Names: Ansamitocin P-0, ZWJ9A2AJ2U
CAS No: 57103-68-1
PubChem CID: 9915934
Mol Formula: C28H37ClN2O8
Mol Weight: 565.10 g/mol
IUPAC Name: (1S,2R,3S,5S,6S,16E,18E,20R,21S)-11-chloro-6,21-dihydroxy-12,20-dimethoxy-2,5,9,16-tetramethyl-4,24-dioxa-9,22-diazatetracyclo[19.3.1.110,14 -Show More
Alternate Use: API Intermediate
Commercial / Development Status: Commercial APIs
Source / Manufacturing Origin: Semi-synthetic APIs
API Description: Maytansinol, also known as Ansamitocin P-0, is a potent microtubule-depolymerizing agent that has demonstrated antitumor activity. It's used in research as a precursor for creating maytansinoid antibody-drug conjugates (ADCs), which are being explored as targeted cancer therapies. Maytansinol itself can induce apoptosis and inhibit microtubule assembly.
