Find verified Mafenide acetate API manufacturers, suppliers, and distributors across the globe. Explore companies that offer high-purity Mafenide acetate for pharmaceutical use, along with product details, certifications, and reliable sourcing options. Compare prices, check availability, and connect directly with trusted suppliers for Mafenide acetate API.
Alternate Names: Sulfamilon, RQ6LP6Z0WY, DTXCID0078825, NSC34632
CAS No: 13009-99-9
PubChem CID: 25590
Mol Formula: C9H14N2O4S
Mol Weight: 246.29 g/mol
IUPAC Name: acetic acid;4-(aminomethyl)benzenesulfonamide
API Description: Mafenide Acetate is the acetate salt form of mafenide, a synthetic sulfonamide analog of para-aminobenzoic acid (PABA) with topical anti-infective activity. Mafenide acetate competes with PABA for the bacterial enzyme dihydropteroate synthase, thereby preventing the incorporation of PABA into dihydrofolic acid, thereby interferes with normal folic acid metabolism. As a result, de novo synthesis of pyrimidines, which requires folate metabolites, is impeded and subsequently DNA synthesis is affected. Mafenide acetate is bacteriostatic against many gram-negative and gram-positive organisms, including Pseudomonas aeruginosa and certain strains of anaerobes.
