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Alternate Names: Fortasec, Loperacap, Nu-Loperamide
CAS No: 53179-11-6
PubChem CID: 3955
Mol Formula: C29H33ClN2O2
Mol Weight: 477.0 g/mol
IUPAC Name: 4-[4-(4-chlorophenyl)-4-hydroxypiperidin-1-yl]-N,N-dimethyl-2,2-diphenylbutanamide
API Description: Loperamide is an anti-diarrheal agent that is available as an over-the-counter product for treating diarrhea. The drug was first synthesized in 1969 and used medically in 1976. It is a highly lipophilic synthetic phenylpiperidine opioid that works by binding to mu-opioid receptors on intestinal muscles to decrease intestinal motility and electrolyte loss. Loperamide has a chemical structure that is similar to diphenoxylate and haloperidol; however, loperamide works on mu (μ)-opioid receptors to mediate its pharmacological actions.
