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Alternate Names: Leniolisibum, Leniolisib free base
CAS No: 1354690-24-6
PubChem CID: 57495353
Mol Formula: C21H25F3N6O2
Mol Weight: 450.50 g/mol
IUPAC Name: 1-[(3S)-3-[[6-[6-methoxy-5-(trifluoromethyl)pyridin-3-yl]-7,8-dihydro-5H-pyrido[4,3-d]pyrimidin-4-yl]amino]pyrrolidin-1-yl]propan-1-one
Commercial / Development Status: Commercial APIs
Source / Manufacturing Origin: Synthetic APIs
API Description: Leniolisib is a pyridopyrimidine that is 5,6,7,8-tetrahydropyrido[4,3-d]pyrimidine substituted by [(3S)-1-propanoylpyrrolidin-3-yl]amino and 6-methoxy-5-(trifluoromethyl)pyridin-3-yl groups at positions 4 and 6, respectively. It has a role as an EC 2.7.1.153 (phosphatidylinositol-4,5-bisphosphate 3-kinase) inhibitor and an immunomodulator. It is an aromatic ether, a member of pyridines, an organofluorine compound, a pyridopyrimidine, a secondary amino compound, a member of pyrrolidines and a tertiary carboxamide.
