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Alternate Names: L-Ornithine Phenyl Acetate
CAS No: 952154-79-9
PubChem CID: 44247677
Mol Formula: C13H20N2O4
Mol Weight: 268.31 g/mol
IUPAC Name: (2S)-2,5-diaminopentanoic acid;2-phenylacetic acid
API Description: Ornithine Phenylacetate (OP) is a drug used to treat high ammonia levels (hyperammonemia) in liver disease, primarily for hepatic encephalopathy (HE) (brain dysfunction from liver failure) and liver failure/cirrhosis, by enhancing ammonia removal through glutamine synthesis and excreting it as phenylacetylglutamine (PAGN). It works by providing ornithine for glutamine production and phenylacetate to form PAGN, which is excreted, thus lowering ammonia and improving neurological function in animal models and showing promise in human trials.
