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Alternate Names: Ketanserinum, Ketanserina
CAS No: 83846-83-7
PubChem CID: 3822
Mol Formula: C22H22FN3O3
Mol Weight: 395.4 g/mol
IUPAC Name: 3-[2-[4-(4-fluorobenzoyl)piperidin-1-yl]ethyl]-1H-quinazoline-2,4-dione
Commercial / Development Status: Discontinued
Source / Manufacturing Origin: Synthetic
API Description: Ketanserin is a quinazoline derivative and serotonin (5-hydroxytryptamine, 5HT) receptor subtype 2 (5-HTR2) antagonist with potential antihypertensive and antiplatelet activities. Following administration, ketanserin binds to and inhibits the signaling mediated by 5-HTR2, which inhibits serotonin-dependent vasoconstriction and platelet activation.
