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Alternate Names: Ibandronate sodium hydrate, Ibandronate sodium
CAS No: 138926-19-9
PubChem CID: 23663991
Mol Formula: C9H24NNaO8P2
Mol Weight: 359.23 g/mol
IUPAC Name: sodium;hydroxy-[1-hydroxy-3-[methyl(pentyl)amino]-1-phosphonopropyl]phosphinate;hydrate
Therapeutic use: Anti-osteoporosis agents
Drug Class: Bisphosphonates
Commercial / Development Status: Commercial APIs
Source / Manufacturing Origin: Synthetic APIs
API Description: Ibandronate Sodium is the sodium salt form of ibandronic acid, a synthetic nitrogen-containing bisphosphonate. Ibandronic acid inhibits farnesyl pyrophosphate synthase, resulting in a reduction in geranylgeranyl GTPase signaling proteins and apoptosis of osteoclasts. This agent increases bone mineral density, decreases bone remodeling, inhibits osteoclast-mediated bone resorption, and reduces metastases-related and corticosteroid-related bone pain.
