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Alternate Names: Frovatriptan succinate hydrate, Frovatriptan Succinate monohydrate, Frovelan, Migard
CAS No: 158930-17-7
PubChem CID: 152943
Mol Formula: C18H25N3O6
Mol Weight: 379.4 g/mol
IUPAC Name: butanedioic acid;(6R)-6-(methylamino)-6,7,8,9-tetrahydro-5H-carbazole-3-carboxamide;hydrate
Therapeutic use: Central Nervous System (CNS) Agents
Drug Class: Serotonin agents, Triptans
Commercial / Development Status: Commercial APIs
Source / Manufacturing Origin: Synthetic APIs
API Description: Frovatriptan Succinate is the succinate salt form of frovatriptan, a synthetic triptan with serotonin (5-HT) receptor agonist activity. Frovatriptan succinate binds selectively and with high affinity to 5-HT 1B and presynaptic 5-HT 1D receptors in the extracerebral and intracranial arteries. This leads to an inhibition of serotonin activity and results in vasoconstriction of the painfully dilated blood vessels during migraine attack. Frovatriptan succinate is indicated for the acute treatment of migraine.
