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Alternate Names: Daporinad
CAS No: 658084-64-1
PubChem CID: 6914657
Mol Formula: C24H29N3O2
Mol Weight: 391.5 g/mol
IUPAC Name: (E)-N-[4-(1-benzoylpiperidin-4-yl)butyl]-3-pyridin-3-ylprop-2-enamide
API Description: Daporinad is a small molecule with potential antineoplastic and antiangiogenic activities. Daporinad binds to and inhibits nicotinamide phosphoribosyltransferase (NMPRTase), inhibiting the biosynthesis of nicotinamide adenine dinucleotide (NAD+) from niacinamide (vitamin B3), which may deplete energy reserves in metabolically active tumor cells and induce tumor cell apoptosis.
