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Alternate Names: Esaxerenonum, Esaxerenona
CAS No: 1632006-28-0
PubChem CID: 25052023
Mol Formula: C22H21F3N2O4S
Mol Weight: 466.5 g/mol
IUPAC Name: 1-(2-hydroxyethyl)-4-methyl-N-(4-methylsulfonylphenyl)-5-[2-(trifluoromethyl)phenyl]pyrrole-3-carboxamide
API Description: Esaxerenone (brand name Minnebro) is a non-steroidal mineralocorticoid receptor (MR) blocker used primarily for treating hypertension (high blood pressure) in Japan, showing benefits in essential hypertension, diabetes-related hypertension, and chronic kidney disease (CKD). It works by blocking mineralocorticoid receptors, promoting sodium excretion without potassium loss, and offering organ protection, especially for kidneys and heart, often used with other drugs like SGLT2 inhibitors or CCBs.
