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Alternate Names: UNII-J2KEK56NRS
CAS No: 2415661-92-4
PubChem CID: 135228365
Mol Formula: C65H93N17O16S2
Mol Weight: 1432.7 g/mol
IUPAC Name: (2S,3R)-2-[[(4R,7S,10S,13R,16S,19R)-10-(4-aminobutyl)-7-[(1R)-1-hydroxyethyl]-16-[(4-hydroxyphenyl)methyl]-13-(1H-indol-3-ylmethyl)-6,9,12,15,18-penta -Show More
API Description: Dotamtate is a somatostatin‑receptor–targeting peptide ligand that serves as the drug substance (ligand component) for the radiopharmaceutical 212Pb‑DOTAMTATE (AlphaMedix), an investigational targeted alpha‑emitter therapy for SSTR‑positive neuroendocrine tumors. As a standalone drug substance, Dotamtate is essentially a modified octreotate peptide bearing a macrocyclic chelator (DOTAM) for stable complexation with lead‑212 or other metals.
