Find verified Dorzagliatin API manufacturers, suppliers, and distributors across the globe. Explore companies that offer high-purity Dorzagliatin for pharmaceutical use, along with product details, certifications, and reliable sourcing options. Compare prices, check availability, and connect directly with trusted suppliers for Dorzagliatin API.
Alternate Names: Sinogliatin, HuaTangNing, Dorzagliatinum
CAS No: 1191995-00-2
PubChem CID: 57920094
Mol Formula: C22H27ClN4O5
Mol Weight: 462.9 g/mol
IUPAC Name: (2S)-2-[3-(2-chlorophenoxy)-5-oxo-2H-pyrrol-1-yl]-N-[1-[(2R)-2,3-dihydroxypropyl]pyrazol-3-yl]-4-methylpentanamide
Therapeutic use: Antidiabetic Agents
Commercial / Development Status: Commercial
Source / Manufacturing Origin: Synthetic
API Description: Dorzagliatin is a novel oral medication used primarily for treating Type 2 Diabetes Mellitus, approved in China as monotherapy or with metformin, that works by activating glucokinase to improve the body's glucose control, enhancing insulin secretion and sensitivity, reducing blood sugar, and potentially offering benefits for diabetic kidney disease and even GCK-MODY. It improves HbA1c, fasting, and postprandial glucose levels, and shows promise for restoring pancreatic beta-cell function and halting disease progression in diabetes.
