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Alternate Names: Sodium hydrogen valproate, Depakote Sprinkles, Epival
CAS No: 76584-70-8
PubChem CID: 23663956
Mol Formula: C16H31NaO4
Mol Weight: 310.40 g/mol
IUPAC Name: sodium;2-propylpentanoate;2-propylpentanoic acid
Therapeutic use: Anticonvulsants
Drug Class: Mood stabilizers, Psychotropic agents
Commercial / Development Status: Commercial
Source / Manufacturing Origin: Synthetic
API Description: Divalproex sodium is a stable coordination compound comprised of sodium valproate and valproic acid with anticonvulsant and antiepileptic activities. Divalproex dissociates to the valproate ion in the gastrointestinal tract. This agent binds to and inhibits gamma-aminobutyric acid (GABA) transaminase and its anticonvulsant activity may be exerted by increasing brain concentration of GABA and by inhibiting enzymes that catabolize GABA or block the reuptake of GABA into glia and nerve endings. Divalproex may also work by suppressing repetitive neuronal firing through inhibition of voltage-sensitive sodium channels.
